With the arrest of Le Bon, Dupin becomes interested in pursuing the investigation and obtains permission to search the crime scene. Dupin is eager to survey the setting because the newspaper reports portray the apartment as impossible to escape from the inside, which makes the case so mysterious. Dupin suggests that the police have been so distracted by the atrocity of the murder and the apparent lack of motive that, while they have been attentive to what has occurred, they have failed to consider that the present crime could be something that has never occurred before. Producing two pistols, Dupin reveals that he awaits the arrival of a person who will prove his solution to the crime. 

Dupin also names those elements of the crime scene that he believes the police have mishandled. For example, the shrill voice remains unidentifiable in its gender and its nationality, but it also cannot be identified as emitting words at all, just sounds. He also explains that the police have overlooked the windows in the apartment, which operate by springs and can be opened from the inside. Though the police believe the windows to be nailed shut, Dupin discovers a broken nail in one window, which only seemed to be intact. Dupin surmises that someone could have opened the window, exited the apartment, and closed the window from the outside without raising suspicion. 

Dupin also addresses the mode of entry through the windows. The police imagine that no suspect could climb up the walls to the point of entry. Dupin hypothesizes that a person or thing of great agility could leap from the lightning rod outside the window to the shutters of the window. Dupin surmises that no ordinary human could inflict the beating that Madame L’Espanaye suffered. The murderer would have to possess superhuman strength and inhuman ferocity. To satisfy the confusion of the narrator, Dupin points out that the hair removed from Madame L’Espanaye’s fingers was not human hair. After drawing a picture of the size and shape of the hand that killed the two women, Dupin reveals his solution. The hand matches the paw of an orangutan.